Description
The Hedrin 4% Lotion Spray is the same dimeticone 4% head lice treatment as the classic lotion, in a 120ml pump-spray bottle. The spray puts the product directly onto the scalp, which is the part that actually matters — and the part that is hardest to reach through long or thick hair.
Why the spray, not the bottle?
Head lice live and lay their eggs close to the scalp, not along the length of the hair. So the whole job is getting enough product down to the roots across the entire head. Poured lotion tends to soak into the mid-lengths on the way, which is fine on a short crop and frustrating on hair past the shoulders.
The pump spray lets you part the hair in sections and apply straight onto the scalp, so you use the product where it works. Parents of children with long or thick hair are usually the ones who find the difference worth it. The formulation, contact time and repeat schedule are identical to the 150ml Hedrin 4% Lotion — only the applicator changes.
How Hedrin works
Dimeticone is a silicone oil, not an insecticide. It coats the lice in a film that blocks their breathing and their ability to manage water, so they cannot survive. Because the action is physical rather than chemical, there is no known mechanism for lice to develop resistance to it — unlike the older neurotoxic treatments, which large numbers of UK lice are now resistant to. If a product you used a few years ago has stopped working, that is usually why.
How to use the lotion spray
- Apply to dry hair. Wet hair dilutes it and stops it coating properly.
- Part the hair into sections and spray directly onto the scalp, working across the whole head.
- Comb or work it through with your fingers from roots to tips so every hair is covered.
- Let the hair dry naturally — no hairdryer.
- Leave on for at least 8 hours, or overnight, then wash out with normal shampoo.
- Repeat the full treatment after 7 days.
Don’t be sparing. Under-application is one of the two main reasons treatment fails; the other is skipping the day-7 repeat.
Why the second application matters
Eggs that survive the first treatment hatch within about a week. If you stop after one application, that new generation makes it look as though the lice came back — when in fact they were never fully cleared. The repeat on day 7 is what finishes the job, so book it in when you do the first one.
How much do you need for long hair?
A 120ml bottle covers roughly one application on long, thick hair, or two on shorter hair. Since a proper course is two full applications a week apart, work out what you need before you start rather than running out halfway through the second treatment — a half-dose is close to no dose.
Safety and warnings
- Suitable from 6 months of age; under 6 months only under medical supervision.
- Flammable — treated hair burns readily. Keep away from naked flames, cigarettes, gas hobs, straighteners and hairdryers while it is on the hair.
- Avoid the eyes; rinse with plenty of water if it gets in.
- Stop if a rash or other sign of sensitivity develops. Scalp flaking or irritation can occur.
Checking whether treatment worked
Detection comb wet, conditioned hair a couple of days after the second application. Empty egg cases stay glued to the hair as it grows and are not evidence of an active infestation — look for live, moving lice. There is no need to wash bedding or bag soft toys: lice spread by prolonged head-to-head contact and do not survive long off a scalp. See the full antiparasitic range, including Ovex for threadworm.
Buy Hedrin Lotion Spray online
Bury Healthcare Online is a GPhC-registered UK pharmacy (registration 1126145). Our pharmacy team can advise on how much you need for your child’s hair length and on what to do if lice persist after a full course.
Always read the instructions for use before applying. If live lice remain after both applications, speak to your pharmacist.
Medically reviewed by Hassan Khan, MPharm, Independent Prescriber — Superintendent Pharmacist, Bury Healthcare Online (GPhC-registered pharmacy 1126145). Last reviewed: July 2026.




