Weight management treatment guides
Factual, pharmacist-reviewed guides to the licensed weight-management medicines. These pages explain what the evidence shows. They are not offers of treatment, and all the medicines discussed are prescription-only.
Foundayo (orforglipron): the oral GLP-1 tablet now authorised in the UK
What the MHRA authorised on 10 August 2026, how it is dosed, and what is still unknown.
Orforglipron side effects: what the evidence shows, and how they are managed
Trial frequencies at each dose, discontinuation rates, practical management, and the CYP3A4 interactions.
Orforglipron cost and availability in the UK
What has been established, the NICE timetable, and why the figures circulating online should be treated with caution.
Weight-loss pill or injection? Orforglipron compared with tirzepatide, semaglutide and oral semaglutide
Route, dosing, storage and interactions — and why the headline percentages cannot fairly be compared.
Reviewed by Hassan Khan, Clinical Pharmacist and Independent Prescriber · Bury Healthcare Online · GPhC registration 2067135